Synthesis of organic compounds using deformable gel in porous ri

Details Synthesis of organic compounds using deformable gel in porous ri Synthesis of organic compounds using deformable gel in porous ri

1986-06-09

1988-06-28

Phillips, Delbert R.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

530334, C08F28300, A61K 3702

Patent

active

047539852

ABSTRACT:
The present invention relates to the synthesis of chemical compounds and more particularly to the synthesis of organic compounds, for example, peptides and oligonucleotides.
The invention provides a composite material for use in the synthesis of organic compounds comprising a support material and, supported on the support material, an organic compound synthesizing substance.
It is preferred that the organic compound synthesizing substance is a gel (e.g. a dimethylacrylamide co-polymer gel).
The invention also provides a method for preparing a composite material for use in the synthesis of organic compounds and a method for the synthesis of organic compounds.

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Atherton et al., J. Am. Chem. Soc., 97: 22, 6584-5 (1975).
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Brown et al., J. Chem. Soc. Chem. Comm., 1093-1095 (1980).
Brown et al., J. Chem. Soc. Perkin I, 75-82 (1983).
Atherton et al., "Synthesis of a 21-Residue Fragment of Human Proinsulin by the Polyamide Solid Phase Method", Hoppe-Seyler's Z. Physiol. Chem., Bd. 362, S. 833-839, Jul. 1981.

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