Synthesis of optically-active phosphono analogs of succinates

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus esters

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558179, C07F 938, C07F 940

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active

054730929

ABSTRACT:
The present invention relates to catalytic asymmetric hydrogenation of phosphorus analogs of itaconic acid to synthesize novel optically active phosphono succinates.

REFERENCES:
patent: 4939288 (1990-07-01), Talley
Vineyard, B. D. et al. "Asymmetric Hydrogenation. Rhodium Chiral Bisphosphine Catalyst" J. Am. Chem. Soc. 1977, 99(18), 5946-52.

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