Synthesis of novel immunosuppressive cyclosporin analogs with mo

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides

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Details

530334, 530335, 530317, 514 11, A61K 3702, A61K 3700, C07K 500, C07K 700

Patent

active

052141306

ABSTRACT:
New immunosuppressive cyclosporin analogs are disclosed consisting of [dehydro-Ala].sup.8 cyclosporins and derived therefrom cyclosporins having a sulfur containing amino acid at position-8.

REFERENCES:
patent: 4703033 (1987-10-01), Seebach
patent: 4771122 (1988-09-01), Seebach
patent: 4885276 (1989-12-01), Witzel

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