Synthesis of novel azo-dyes and their use in oligonucleotide...

Organic compounds -- part of the class 532-570 series – Organic compounds – Azo

Reexamination Certificate

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C534S774000, C534S777000, C435S006120

Reexamination Certificate

active

07956169

ABSTRACT:
The invention provides a novel group of azo quencher compositions that are useful as quenchers of fluorescence and to methods for making and using them. The quenchers contain an azo bond and 1,3,3-trimethyl-2-methyleneindoline ring system. The quenchers can be derivatized to facilitate their conjugation to a variety of biologically relevant compounds, including lipids, nucleic acids, peptides, proteins, and the like.

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