Synthesis of nicotinic analogs

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546194, 546257, 514318, 514334, C07D40104

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active

058409068

ABSTRACT:
A process for synthesis of anabaseine using nicotinoyl piperidone salt having the formula ##STR1## wherein R.sub.1 and R.sub.2 are lower alkyl and M is a group I alkaline metal.

REFERENCES:
patent: 5602257 (1997-02-01), Zoltewicz et al.
Watanabe et al. "Preparation of pyridine derivative as intermediates for anabaseine" CA 125:142557, 1996.
Bradley et al. "Synthetic studies on meptanol. . . ." CA 94:103141, 1980.
Hamlet et al. "1-(dialylaminomethyl)-azetidin-2-on2s. Intermediates in a highly . . . " Can. J. chem. v.61, pp. 411-415, 1983.
McOmie "Protetive groups in organic chemistry" Plenum Press, pp. 43, 49, 52, 62, 74, 75, 1973.
Sullivan et al. "The self condensation reaction . . . " CA 87:23383, 1977.

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