Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter
Reexamination Certificate
2005-03-23
2010-06-29
Le, H. (Holly) T (Department: 1794)
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Particulate matter
C428S403000, C428S407000, C435S103000, C436S526000, C977S773000, C977S783000, C977S824000, C977S830000, C977S834000, C977S838000
Reexamination Certificate
active
07745001
ABSTRACT:
Negatively charged luminescent CdSe—ZnS quantum dots (QDs) were successfully incorporated into novel luminescent glyconanospheres averaging around 190 nm in diameter through electrostatic interactions with carboxymethyldextran (CM-dextran) and polylysine. The glyconanospheres preferably contain as well carboxyl-modified iron oxide nanocrystals. In addition to electrostatic attraction between the negatively charged dextran, the negatively charged CdSe—ZnS QDs (and negatively charged iron oxide nanocrystals, if present), and the positively charged polylysine, covalent amide bonds were introduced to cross link the QDs (and negatively charged iron oxide nanocrystals, if present) with the polysaccharide matrix to further stabilize the glyconanospheres. The dextran residues on the surface of the nanospheres show high affinity toward the glucose binding protein-Concanavalin A (Con A). As a result, these luminescent CdSe—ZnS QD incorporated glyconanospheres are a useful tool for studying carbohydrate-protein interactions that are critical steps in bacterial and viral infection.
REFERENCES:
patent: 5961507 (1999-10-01), Widlund
patent: 6322901 (2001-11-01), Bawendi et al.
patent: 6447887 (2002-09-01), Claus et al.
patent: 6548171 (2003-04-01), Barbera-Guillem et al.
patent: 6548264 (2003-04-01), Tan et al.
patent: 6630307 (2003-10-01), Bruchez et al.
patent: 6680211 (2004-01-01), Barbera-Guillem et al.
patent: 6699723 (2004-03-01), Weiss et al.
patent: 6773823 (2004-08-01), O'Connor et al.
patent: 6906339 (2005-06-01), Dutta
patent: 7172791 (2007-02-01), Treadway et al.
patent: 7214427 (2007-05-01), Huang et al.
patent: 7261940 (2007-08-01), Klimov et al.
patent: 7534489 (2009-05-01), Ying et al.
patent: 2003/0157327 (2003-08-01), Barbera-Guillem et al.
patent: 2003/0178309 (2003-09-01), Huang et al.
patent: 2006/0068203 (2006-03-01), Ying et al.
patent: 2006/0118757 (2006-06-01), Klimov et al.
Salgueirino-Maceira et al., Composite Silica Spheres with Magnetic and Luminescent Functionalities, Adv. Funct. Mater., vol. 16, Issue 4, (2006).
Sou-Yee Mak et al.,Fabrication of Magnetic Luminescent Nanocomposites via Adsorption-Precipitation of metal Ions on Sulfonated Iron Oxide Nanoparticles, Chemistry Letter, vol. 35, No. 10, pp. 1116-1117, (2006).
Dosev et al., Magnetic/luminescent core/shell particles synthesized by spray pyrolysis and their application in immunoassays with internal standard, Nanotechnology 18 (2007) 055102 (6pp).
Gu et al., “Facile One-Pot Synthesis of Bifunctional Heterodimers of Nanoparticles: A Conjugate of Quantum Dot and Magnetic Nanoparticles”, J. Am. chem. Soc. 2004, 126, 5664-5665, (published on Web Apr. 20, 2004).
Chen et al, Synthesis of Glyconanospheres Containing LUminescent CdSe-ZnS Quantum Dots, Nano Lett., 2003, vol. 3, No. 5, 581-584.
Chen Yongfen
Rosenzweig Zeev
Wang Desheng
Garvey, Smith Nehrbass & North, L.L.C.
Le H. (Holly) T
Nehrbass Seth M.
University of New Orleans Research and Technology Foundation, In
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