Synthesis of N-disubstituted amides by reaction of amides with c

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564153, 564159, 564201, 564203, 564204, 564207, 564218, 564219, 564182, 564183, 564184, 554 68, C07C23112

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051188465

ABSTRACT:
Disclosed is a method which comprises introducing into a reaction zone a feed which comprises a hydroxyl compound reactant, R"OH at least one amide reactant selected from R--CONH.sub.2 and R--CONHR', and a Lewis base as catalyst, thereby reacting R"OH with said amide reactant to produce a reaction mixture containing at least one disubstituted amide selected from R--CONR".sub.2 and R--CONR'R", wherein

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