Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
2008-11-14
2011-12-13
Anderson, Rebecca (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
active
08076476
ABSTRACT:
Morpholino compounds are provided having the structure:whereR1is selected from the group consisting of lower alkyl, di(lower alkyl)amino, and phenyl;R2is selected from the group consisting of lower alkyl, monocyclic arylmethyl, and monocyclic (aryloxy)methyl;R3is selected from the group consisting of triarylmethyl and hydrogen; andY is selected from the group consisting of: a protected or unprotected hydroxyl or amino group; a chlorophosphoramidate group; and a phosphorodiamidate linkage to the ring nitrogen of a further morpholino compound or a morpholino oligomer. Such compounds include doubly protected morpholino guanine (MoG) monomers. Also described is their use in synthesis of morpholino oligomers.
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Li Yongfu
Reeves Matthew Dale
Weller Dwight D.
Anderson Rebecca
AVI BioPharma Inc.
Seed IP Law Group PLLC
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