Synthesis of isochromans and their derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549409, 549410, 504292, C07D31104, C07D31106, C07D31122, A01N 4316

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active

059228890

ABSTRACT:
Isochromans and their derivatives have been chemically synthesized. These compounds possess significant phytotoxic activity which may be used as a biodegradable contact herbicide. The synthetic method allows for economic production of these herbicides.

REFERENCES:
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Cutler et al., "Ruakuric Acid: A Natural Product from Aspergillus Fumigatus", Phytochemistry, vol. 00, No. 00, pp. 1-00, 1996.
Cox et al., "A New Isochroman Mycotoxin Isolated from Penicillium steckii", J. Agric. Food Chem., vol. 27 (1979).
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Greene, Protective Groups in Organic Synthesis, pp. 88-92, 1991.
Ziegler et al., "Mild Method for the Esterification of Fatty Acids", Synthetic Communications, vol. 9(6), pp. 539-543 (1979).
Holton and Nelson, "A New Protecting Group for Phels: Phenylthiomethyl (PTM) Ethers", Synthetic Communications, vol. 10(12), pp. 911-914 (1980).
Deady et al., "Preparation of Some Chromans from 1,3-diaryloxy-propanes", J. Chem. Soci., pp. 2094-2095 (1963).

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