Synthesis of ioversol

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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C07C23305

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054897084

ABSTRACT:
The reduction of the O-alkyl isomer content of 5-[N-(2-acetoxyethyl)acetoxyacetamido]-N,N'-bis(2,3-diacetoxypropyl)-2,4,6 -triiodoisophthalamide to thereby reduce and/or eliminate the production of impurities comparatively more difficult to remove during the purification of crude ioversol.

REFERENCES:
patent: 503587 (1991-07-01), Sovak et al.
patent: 5004835 (1991-04-01), Blaszkiewicz et al.
patent: 5019371 (1991-05-01), Lin et al.
patent: 5043152 (1991-08-01), Schaefer et al.

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