Synthesis of fluorinated ethers

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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C07C 4122, C07C 4312

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060546263

ABSTRACT:
Fluorinated ethers of the formula: ##STR1## wherein R is hydrogen, fluorine, alkyl of 1 to 6 carbon atoms, or fluoroalkyl of 1 to 6 carbon atoms, R' is hydrogen, alkyl of 1 to 6 carbon atoms, or fluoroalkyl of 1 to 6 carbon atoms, and R" is fluorine, alkyl of 1 to 6 carbon atoms or fluoroalkyl of 1 to 6 carbon atoms, e.g. Desflurane, are prepared by fluorinating a corresponding ether of formula: ##STR2## with a solid transition metal fluoride fluorinating agent such as cobaltic fluoride.

REFERENCES:
patent: 2614129 (1952-10-01), McBee et al.
patent: 3897502 (1975-07-01), Russell et al.

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