Synthesis of ferrocenyl phenyltropane analogs and their radio-tr

Details Synthesis of ferrocenyl phenyltropane analogs and their radio-tr Synthesis of ferrocenyl phenyltropane analogs and their radio-tr

1996-06-13

1997-12-23

Kight, John

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

546124, 546125, 424 165, A61K 5100, A61M 3614

Patent

active

057004463

ABSTRACT:
Neuroprobes that include rhenium, manganese, and technetium for use in mapping monoamine reuptake sites are disclosed. Non-radioactive tricarbonylrheniumcyclopentadienyl (TRCp) or non-radioactive tricarbonylmanganesecyclopentadienyl (TMCp) phenyltropane analogs are synthesized for use as testing surrogates for radioactive technetium congeners. Ferrocenyl analogs of phenyltropane are disclosed as useful precursors for the preparation of novel tricarbonyltechnetiumcyclopentadienyl (TTCp) phenyltropane analogs in radioactive form.

REFERENCES:
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