Synthesis of deoxybiotinyl hexamethylenediamine-dota

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07851621

ABSTRACT:
A process for the synthesis of deoxybiotinyl hexamethylenediamine0-DOTA is herein described. Said process comprises reacting biotinyl hexamithylenediamine with tri-t-butyl DOTA in the presence of benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, as the condensing agent, and triethylamine, as a base.

REFERENCES:
patent: 2005/0085630 (2005-04-01), Olejnik et al.
patent: WO 02/066075 (2002-08-01), None
Giuseppina Sabatino, et a., A New Biotin Derivative-Dota Conjugate as a Candidate . . . , J. Med. Chem. vol. 46, pp. 3170-3173, 2003.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Synthesis of deoxybiotinyl hexamethylenediamine-dota does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of deoxybiotinyl hexamethylenediamine-dota, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of deoxybiotinyl hexamethylenediamine-dota will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4211014

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.