Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus containing
Patent
1996-04-29
1998-01-20
Dees, Jose G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus containing
C07F 950
Patent
active
057103402
ABSTRACT:
Phosphines having two aryl groups and one alkyl-substituted cycloalkyl group bonded to a phosphorus atom are formed by reacting an alkali metal diarylphosphide with a monoalkyl- or polyalkyl-substituted cycloalkyl mesylate or tosylate in which an alkyl group is in the 2-position, in a liquid reaction medium in which these reactants are soluble. This process avoids complications associated with prior known process technology for producing such phosphines. The phosphines are useful as ligands for making noble metal catalysts.
REFERENCES:
patent: 2902517 (1959-09-01), Schmerling
patent: 4618720 (1986-10-01), Bay
patent: 4668823 (1987-05-01), Murray
patent: 5288912 (1994-02-01), Devon
Aguiar et al., "Lithium Diphenylphosphide: A Convenient Source and Some Reaction", JOC Mar. 1962, vol. 27, pp. 1001-1004.
Toth et al., "Aspects of the Cleavage of Phosphines with Potassium: Synthesis and Reactivity of Lithium and Potassium Bis(p-(dimethylamino)phenyl)phosphide", Organometallics 1990, vol. 9, No. 3, pp. 675-680.
Rossi et al., "Reaction of 1-Bromoadamantane with Diphenylphosphide and Diphenylarsenide Ions by the SRN1 Mechanism. Facile Nucleophilic Substitution at the Bridegehead Position", J Org Chem 1982, vol. 47, No. 24, pp 4654-4657.
Aguiar et al., "The Reaction of Lithium Diphenyphosphide and Simple Aryl Halides", Aug. 1963, vol. 28, pp 2091-2093.
Tsvetkov et al., "A Simple Synthesis and Some Synthetic Applications of Substituted Phosphide and Phosphinite Anions", Synthesis, Mar. 1986, pp. 198-208.
Hayashi et al., "Catalytic Asymmetric Hydroformylation by the Use of Rhodiumcomplexes of Chiral Bidentate Phosphorus Ligands Bearing Saturated Ring Skeletons", Sep. 1979, Bulletin of the Chemical Society of Japan, vol. 52, No 9, pp 2605-2608.
Morrison et al., "Synthesis of Menthyl-and Neomenthydiphenylphosphine. Epimeric, Chiral, Tertiary Phosphine Ligands for Asymmetric Synthesis", J Org Chem, vol 39, No 2, 1974, pp. 270-272.
Wittenberg and Gilman, "Lithium Cleavages of Triphenyl Derivativess of Some Group Vb Elements in Tetrahydrofuran", J Org Chem vol 23, pp. 1063-1065, Jul. 1958.
Kuchen and Buchwald, "Reactions of diphenylphosphine Sodium", Angew Chem 69, pp 307-308 (1957)-Abstract Attached.
Albemarle Corporation
Dees Jos,e G.
Pippenger Philip M.
Vollano Jean F.
LandOfFree
Synthesis of cycloalkyldiarylphosophines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Synthesis of cycloalkyldiarylphosophines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of cycloalkyldiarylphosophines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-726888