Synthesis of CCR5 receptor antagonists

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

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C544S364000, C544S335000

Reexamination Certificate

active

07728135

ABSTRACT:
The present invention is directed to the synthesis of 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine], and intermediates therefor from readily available starting materials by a novel route.

REFERENCES:
patent: 6720325 (2004-04-01), Miller
patent: WO96/26196 (1996-08-01), None
International Search Report for PCT/US2006/000262; mailed Jun. 21, 2006.

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