Synthesis of beta-lactams from azetidine carboxylic acid esters

Details Synthesis of beta-lactams from azetidine carboxylic acid esters Synthesis of beta-lactams from azetidine carboxylic acid esters

1977-12-29

1980-02-26

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603407, 2603409R, 2603303, 26032613B, 260687R, C07D20508, C07D40306, C07D40906, C07D40706

Patent

active

041905792

ABSTRACT:
Azetidine carboxylic acid esters are converted into enol silyl ethers which, as enamino ketene acetals, undergo ready oxidative cleavage of the ethylenically unsaturated double bond, e.g. by dye-sensitized photo-oxygenation, to form beta-lactams. The beta-lactams and substitution products thereof are useful intermediates in the synthesis of biologically active lactams.

REFERENCES:
Foote et al., Tet. Letters 1968, pp. 3267-3270.
Haber, Tet. Letters, 1968, pp. 3271-3272.
Foote et al., Tet. Letters, 1975, pp. 1247-1250.

Affiliated with

Also associated with

Rating

Synthesis of beta-lactams from azetidine carboxylic acid esters does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of beta-lactams from azetidine carboxylic acid esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of beta-lactams from azetidine carboxylic acid esters will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2112726