Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-12-08
2000-12-26
Seaman, D. Margaret
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549388, 549398, 549469, 558423, 568630, 568631, 568657, C07D31300, C07D31906, C07D31192, C07D25500, C07D 4320
Patent
active
061662267
ABSTRACT:
A method for preparing an aryl ether compound is provided in which an alcohol is reacted with an aromatic compound in the presence of a base, and a transition metal catalyst selected from the group consisting of platinum and nickel to form an aryl ether. The aromatic compound comprises an activated substituent, X, said activated substituent being a moiety such that its conjugate acid HX has a pKa of less than 5.0. The catalyst is preferably a soluble palladium complex in the presence of supporting ligands.
REFERENCES:
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Buchwald Stephen L.
Palucki Michael
Wolfe John P.
Gordon Dana M.
Massachusetts Institute of Technology
Seaman D. Margaret
Vincent Matthew P.
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