Synthesis of annamycin

Details Synthesis of annamycin Synthesis of annamycin

1997-07-22

1999-11-02

Peselev, Elli

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 185, C07H 100, C07H 1527

Patent

active

059773278

ABSTRACT:
An improved method for synthesis of Annamycin is described. The synthesis relies upon a method of selectively deacetylating the Annamycin precursor and purification of the deacetylated product by a filtration step. In addition, the method includes an improved method for desilylating the Annamycin precursor that utilizes acidic conditions. Lastly, improved purification methods of the final Annamycin product are disclosed.

REFERENCES:
patent: 4537882 (1985-08-01), Horton et al.

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