Synthesis of aminoarylboronic esters and substituted...

Details Synthesis of aminoarylboronic esters and substituted... Synthesis of aminoarylboronic esters and substituted...

2005-10-25

2005-10-25

Killos, Paul J. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Boron containing

Reexamination Certificate

active

06958420

ABSTRACT:
A process is described for synthesizing aminoarylboronic esters of the general formulawherein R, R2, and R3are each an alkyl, aryl, vinyl, alkoxy, carboxylic esters, amides, or halogen; Ar is any variety of phenyl, naphthyl, anthracyl, heteroaryl; and R1is alkyl, hydrogen, or aryl. The aminoarylboronic esters are produced via the metal-catalyzed coupling of arylboronic esters of the general formulawherein R and R1are any non-interfering group and X is chloro, bromo, iodo, triflates, or nonaflates to amines (primary and secondary). In particular, a process is described for the synthesis of the aminoarylboronic esters via a step-wise or tandem process in which one catalytic event is a metal-catalyzed borylation and the other catalytic event is a metal-catalyzed amination.

REFERENCES:
patent: WO 2000015213 (2000-03-01), None
patent: WO 2000077001 (2000-12-01), None
patent: WO 2001010868 (2001-02-01), None
patent: WO 2001097786 (2001-12-01), None
Staab.Heinx A. et al Justus Liebigs Annalen de Chemie (1971), 753, 80-91.
Klis, Tomasz et al , Main Group Metal Chemistry (20020 25 (8), 479-484.

Affiliated with

Also associated with

Rating

Synthesis of aminoarylboronic esters and substituted... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of aminoarylboronic esters and substituted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of aminoarylboronic esters and substituted... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3490653