Synthesis of alpha-amino acids

Details Synthesis of alpha-amino acids Synthesis of alpha-amino acids

1981-06-29

1983-02-01

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562443, 562445, 562475, 2604657, 260465G, 260465E, 2604655R, C07C 9910

Patent

active

043717055

ABSTRACT:
A method for synthesizing alpha amino acids proceding through novel intermediates of the formulas: R.sub.1 R.sub.2 C(OSOCl)CN, R.sub.1 R.sub.2 C(Cl)CN and [R.sub.1 R.sub.2 C(CN)O].sub.2 SO wherein R.sub.1 and R.sub.2 are each selected from hydrogen monovalent substituted and unsubstituted hydrocarbon radicals of 1 to 12 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the synthesis methods of the prior art.

REFERENCES:
patent: 2264026 (1941-11-01), Gudgeon et al.
patent: 2331681 (1943-10-01), Hechenbleikner
patent: 2446651 (1948-08-01), Hartung
patent: 2520312 (1950-08-01), Gresham et al.
patent: 2917541 (1959-12-01), Anatol et al.
patent: 3179684 (1965-04-01), Covey et al.
patent: 3215736 (1965-11-01), Guinot
patent: 3243814 (1981-01-01), Pascal et al.
patent: 3272854 (1966-09-01), Covey et al.
patent: 3311534 (1967-03-01), Covey et al.
patent: 3475489 (1969-10-01), de Graaf et al.
patent: 3481970 (1969-12-01), Griffith et al.
Greenstein et al., "Chem. of the Amino Acids", John Wiley & Sons, vol. 1, pp. 698-770 & vol III, pp. 2308-2375 (1981).
Sammes, Chem. Abst., vol. 72, #901102 (1970).
Davis, J. Org. Chem., vol. 43, pp. 3980-3982 (1979).

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