Synthesis of acyloxyalkyl carbamate prodrugs and...

Details Synthesis of acyloxyalkyl carbamate prodrugs and... Synthesis of acyloxyalkyl carbamate prodrugs and...

2011-08-23

2011-08-23

Nolan, Jason M (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C560S115000

Reexamination Certificate

active

08003809

ABSTRACT:
Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

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