Synthesis of acyclic nucleoside derivatives

Details Synthesis of acyclic nucleoside derivatives Synthesis of acyclic nucleoside derivatives

2007-03-13

2007-03-13

Berch, Mark L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

Reexamination Certificate

active

11131646

ABSTRACT:
Novel processes towards the synthesis of the antiviral valomaciclovir stearate in which an esterified guanine acetal is reduced to the corresponding alcohol, reacted with an activated amino acid and N-deprotected. The esterified guanine acetal is prepared from a 9-guanine derivative bearing an acyclic hydroxymethylbutylacetal. The processes are amendable to one-pot reactions.

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