Synthesis of 5-substituted tetrazoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D40306

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040974790

ABSTRACT:
Synthesis of 5-substituted tetrazoles via reaction of an organic nitrile with azide anion is improved by performing the reaction in an amine as solvent and in the presence of an acid-addition salt of the amine as catalyst.

REFERENCES:
patent: 3231574 (1966-01-01), Strycker et al.
patent: 3499900 (1970-03-01), Schut et al.

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