Synthesis of 5-deazariboflavine

Details Synthesis of 5-deazariboflavine Synthesis of 5-deazariboflavine

1983-06-30

1986-01-28

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544313, C07D47104, C07D23954

Patent

active

045672601

ABSTRACT:
A new synthesis of 5-deazariboflavine is afforded by condensing N-D-ribityl-3,4-xylidine with a novel chemical intermediate, 6-chloro-5-formyluracil.

REFERENCES:
patent: 4079069 (1978-03-01), Graham et al.
patent: 4277603 (1981-07-01), Tolman et al.
patent: 4299961 (1981-11-01), De Pasquale et al.
Kazimierczuk et al., Chemical Abstracts, vol. 78, 58339u, (1973).
Yoneda et al., J. Chem. Soc., Perkin Trans. 1, 1976, (16), pp. 1805-1808, (1976).
Kochkanyan et al., Chemical Abstracts, vol. 88, 74409d and Chemical Subject Index, 10 Collective Index, p. 46526CS, (1978).
Yoneda et al., Methods Enzymol. 1980, 66 (Vitam. Coenzymes, Pt. E), pp. 267-277, (1980).

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