Synthesis of 3-aminomethyl-1-propanol, a fluoxetine precursor

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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C564S347000, C564S342000, C514S649000, C514S651000

Reexamination Certificate

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06846957

ABSTRACT:
The present invention concerns a method of synthesizing fluoxetine hydrochloride. The method includes the synthesis of 3-methylamino-1-phenyl-1-propanol by reduction of 1-phenyl-3-methylamino-2-propen-1-one with sodium borohydride and acetic acid.

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