Synthesis of 2-aminobenzophenones

Organic compounds -- part of the class 532-570 series – Organic compounds – Hydroxamate esters or chalcogen analogues thereof

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

540544, 544 63, 548240, 564183, 564184, 564185, 564186, C07C25906

Patent

active

051360853

ABSTRACT:
Process for synthesizing 2-aminobenzophenones such as the following formula (I): ##STR1## wherein X.sup.1 and X.sup.2 are substituents and r and s are 1 or 2, by reacting an anthranilic acid amide e.g. an N-alkoxy-N-alkyl anthranilic acid amide, with a halobenzene in the presence of an alkyllithium reagent.

REFERENCES:
patent: 2893992 (1959-07-01), Sternbach et al.
patent: 3051701 (1962-08-01), Reeder et al.
patent: 3106587 (1963-10-01), Harms et al.
patent: 3136815 (1964-06-01), Reeder et al.
patent: 3202661 (1965-08-01), Brust et al.
patent: 3203990 (1965-08-01), Keller et al.
patent: 3239564 (1965-03-01), Reeder et al.
patent: 3243430 (1966-03-01), Metlesics et al.
patent: 3261870 (1966-07-01), Rachlin et al.
patent: 3267110 (1966-08-01), Pachter et al.
patent: 3297755 (1967-01-01), Sternbach et al.
patent: 3341592 (1967-09-01), Sternbach et al.
patent: 3609146 (1968-11-01), Houlihan
patent: 3651046 (1972-03-01), Dereig et al.
patent: 3686308 (1972-08-01), Ning et al.
patent: 3740442 (1973-06-01), Ott et al.
patent: 4093734 (1978-06-01), Kruger et al.
patent: 4175184 (1979-11-01), Merkle et al.
patent: 4421931 (1983-12-01), Tonne et al.
patent: 4820834 (1988-04-01), Evans et al.
Sternbach, Angew. Chem. Int. Ed. Engl. 1971, 10,34.
Walsh, Synthesis, Sep. 1980, 677-688.
Fryer, "Ligand Interactions at the Benzodazepine", Comprehensive Medicinal Chemistry, vol. 3, 539-566.
Nahm, Tetrahedron Letter, vol. 22, No. 39, 3815-3813 (1981).
Clack et al., Journal of Organic Chemistry, vol. 9, 55-57 (1943).
Stephen V. Frye et al., Journal of Organic Chemistry, vol. 56, 1991.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Synthesis of 2-aminobenzophenones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of 2-aminobenzophenones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of 2-aminobenzophenones will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-779687

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.