Synthesis of...

Details Synthesis of... Synthesis of...

2006-05-09

2008-12-09

Dentz, Bernard (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S167000

Reexamination Certificate

active

07462740

ABSTRACT:
Disclosed is a process for making the compound of formula I:using the compounds of formulas II, Q, and XI or XII:wherein A is selected from the group consisting of Br, Cl and I (with Br being preferred); and R represents (C1-C10)alkyl. Also disclosed are intermediate compounds that are made in the disclosed process.

REFERENCES:
patent: 2003/0204085 (2003-10-01), Taveras et al.
PCT/US2004/011882, PCT International Preliminary Report on Patentability, Mar. 22, 2005.
Abstract No. 115:182817 and 1991-159963 for Japanese 3-95144 Which is Also Submitted Herewith, (1993).
Chakraborty, T.K., et al., “Diastereoselective Strecker Synthesis Using a-Phenylglycinol as Chiral Auxiliary, ”Tetrahedron Letters 32(51):7597-7600, (1991).
Rampino, Louis D., et al., “Applicability of Palladium Synthetic High Polymre Catalysts” J Am Chem Soc 63:3268 (1941).

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