Synthesis for the preparation of 4-amino-4,5-dihydro-2-furancarb

Details Synthesis for the preparation of 4-amino-4,5-dihydro-2-furancarb Synthesis for the preparation of 4-amino-4,5-dihydro-2-furancarb

1987-10-15

1989-04-25

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549475, 556420, 560180, C07D30730

Patent

active

048249742

ABSTRACT:
This application relates to a stereospecific process for preparing specific enantiomers of 4-amino-4,5-dihydro-2-furancarboxylic acid and C.sub.1-6 lower alkyl esters thereof. These compounds are .gamma.-aminobutyric acid transaminase inhibitors useful in the treatment of epilepsy.

REFERENCES:
Oppolzer et al., J. Am. Chem. Soc., vol. 104 (1982) pp. 4978-4979.

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