Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Plant proteins – e.g. – derived from legumes – algae or...
Patent
1992-09-04
1994-02-08
Page, Thurman K.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Plant proteins, e.g., derived from legumes, algae or...
530371, 530372, 530373, 530374, 530375, 530376, 530377, 530378, 530379, 530410, 530417, 530413, 530421, 530810, 530812, 530815, A61K 3578
Patent
active
052849341
ABSTRACT:
The present invention provides a process for preparing a carbohydrate-binding lectin derivative for use as immune modulators or immunoconjugates. The polymer-lectin conjugate produced in accordance with the process is polyethylene glycol Ricinus communis agglutinin I (PEG-RCAI). The lectin is coupled to the polymer by activating the polymer with a coupling agent such as 1,1-carbonyldiimidazole. The polymer-lectin conjugate is biologically active, biocompatible and is expected to be substantially non-immunogenic.
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patent: 4818769 (1989-04-01), Nunberg
patent: 4882226 (1989-11-01), Schutyser
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Health Research , Inc.
Kishore G.
Page Thurman K.
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