Synthesis and immunogenicity of rotavirus genes using a baculovi

Details Synthesis and immunogenicity of rotavirus genes using a baculovi Synthesis and immunogenicity of rotavirus genes using a baculovi

1995-06-07

1998-10-27

Mosher, Mary E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

4351723, 4353201, 4352351, 536 2372, C12N 1546, C12N 1564

Patent

active

058276963

ABSTRACT:
A method to express rotavirus genes in a baculovirus system. Different clones are used to express rotavirus genes for all of the viral proteins. These proteins are isolated in their native conformation. Some of these proteins show antigenic properties and are used to vaccinate human, agricultural animals and pet animals against diarrheal disease. The antigenic proteins are also used to detect the presence of the viral infectious agent either by themselves or in conjunction with antibodies produced against the antigenic proteins.

REFERENCES:
patent: 4853333 (1989-08-01), Hsaio et al.
patent: 4861845 (1989-08-01), Atkinson et al.
Summers, M.D. et al. 1985. In:Genetically Altered Viruses and the Environment, ed. B. Fields, 22 Banbury Report, Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., pp. 319-331.

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