Synthesis and application of alkyl-substituted dibenzofurans as

Details Synthesis and application of alkyl-substituted dibenzofurans as Synthesis and application of alkyl-substituted dibenzofurans as

1994-07-19

1996-05-14

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549388, 549460, A61K 3134

Patent

active

055167900

ABSTRACT:
Provided is a method of inhibiting estrogen activity by administering a biologically active amount of a substituted dibenzofuran or substituted dibenzodioxin.

REFERENCES:
patent: 2500734 (1950-03-01), Abbott, Jr.
patent: 2648684 (1953-08-01), Wenner
patent: 3108121 (1963-10-01), Walsh et al.
patent: 3251859 (1966-05-01), Kulka et al.
patent: 3649651 (1972-03-01), Dobson
patent: 3679704 (1972-07-01), Lester et al.
patent: 3751390 (1973-08-01), Hopps et al.
patent: 3812152 (1974-05-01), Hofer et al.
patent: 3840593 (1974-10-01), Sidwell
patent: 3906007 (1975-09-01), Albrecht et al.
patent: 3920635 (1975-11-01), Nysted
patent: 3935251 (1976-01-01), Dazzi
patent: 3939155 (1976-02-01), Brown
patent: 3989761 (1976-11-01), Gross
patent: 4000203 (1976-12-01), Gross et al.
patent: 4009185 (1977-02-01), Fishel
patent: 4010268 (1977-03-01), Matharu et al.
patent: 4013694 (1977-03-01), Fishel
patent: 4042603 (1977-08-01), Itatani et al.
patent: 4058516 (1977-11-01), Mislin et al.
patent: 4065469 (1977-12-01), Moggi et al.
patent: 4228309 (1980-11-01), Hatcher
patent: 4273771 (1981-06-01), Coussediere
patent: 4293707 (1981-10-01), Richter et al.
patent: 4306098 (1981-12-01), Brooker
patent: 4326882 (1982-04-01), Richter et al.
patent: 4362883 (1982-12-01), Harvey
patent: 4376776 (1983-03-01), Rentzea et al.
patent: 4418068 (1983-11-01), Jones
patent: 4467117 (1984-08-01), Lund et al.
patent: 4486610 (1984-12-01), Lund
patent: 4490562 (1984-12-01), Schreiber et al.
patent: 4608127 (1986-08-01), Sakuma et al.
patent: 4729999 (1988-03-01), Young
patent: 4732904 (1988-03-01), Morgan
patent: 4745109 (1988-05-01), Bednarski et al.
Astroff, et al., The Toxicologist, 9, p. 127 (1989).
Bannister, et al., Toxicology, 54, p. 139 (1989).
Astroff, et al., Toxicol. Appl. Pharmacol, 95, p. 1 (1988).
Romkes, PHd Thesis, Texas A&M Univ., pp. 74, 75, 77-81, 114-118 (88).
Umbreit, et al., Toxicol. Leeters, 42 p. 5 (1988).
Romkes, et al. Toxicol. Appl. Pharmacol., 92, p. 368 (1988).
Holcomb, et al., Biochem. Pharmacol., 37, p. 1535 (1988).
Astroff, et al., Mol. Pharmacol., 33, p. 231 (1988).
Romkes, et al, Toxicol. Appl. Pharmacol., 87, p. 306 (1987).
Gierthy, et al., Cancer Res., 47, p. 6198 (1987).
Bannister, et al., Chemosphere, vol. 16, Nos. 8/9, p. 2739 (1987).
Romkes, et al., Cancer Res., 47, p. 5108 (1987).
Keys, et al., Toxiocl. Letters, 31, p. 151 (1986).
Mason et al., Toxicol, 37, p. 1 (1985).
Denomme, et al., chemc.-Boil. Interactions, 57, p. 175 (1986).
Mason, et al., Toxicol., 37, p. 1 (1985).
Denomme, et al, Molec. Pharmacol, 27, p. 656 (1985).
Safe et al., Agricul. Food Chem., 32, p. 68 (1984).
Shiverick, et al., Toxicol. Appl. Pharmacol, 65, p. 170 (1982).
Kociba, et al, Toxicol. Appl. Pharmacol, 65, p. 170 (1982).
Ramalingan et al., Chlorinated Dioxins Dibenzofurens Perspect., 1986, pp. 485-499.
Gray et al., J. Org. Chem., 41, 2428 (-976).
Denome et al., Chem.-Biol. Interactions, 57, 175-187 (1986) (of record in the parent application).
Astroff et al., C. A., 110:19,507g (1989)--Abstract of Toxical. Appl. Pharmacol., 95(3), 435-433 (1988).
Yao et al., C. A., 111: 168,9646 (1989)-Abstract of Toxxical. Appl. Pharmacol., 100(2), 208-16 (1989).
Harris et al., C.A., 111: 51,858d (1989)-Abstract of Mol. Pharmecol., 35(5), 729-35 (1989).

Affiliated with

Also associated with

Rating

Synthesis and application of alkyl-substituted dibenzofurans as does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis and application of alkyl-substituted dibenzofurans as , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis and application of alkyl-substituted dibenzofurans as will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1895940