Synthesis

Details Synthesis Synthesis

2007-03-13

2007-03-13

Owens, Amelia A. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S299000

Reexamination Certificate

active

10884842

ABSTRACT:
The present invention provides an improved process for the production of [(±)-endo]-4-amino-5-chloro-2-methoxy-N-(1-azabicyclo[3.3.1]non-4-yl)benzamide hydrochloride, compositions thereof, and intermediates thereto.

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Becker, et al., “Synthetic Strategies for the Construction of Enantiometric Azanoradamantanes”,Tetrahedron, 53(1): 1-20, 1997.
Hilgetag, et al., “Organisch-Chemische Experimentierkunst”, 4thEdition, 246-256, 1970.
King, et al., “Substituted Benzamides with Conformationally Restricted Side Chains. 5. Azabicyclo [x.y.z] Derivatives at 5-HT4Receptor Agonists and Gastric Motility Stimulants”,J. Med. Chem.36: 683-689, 1993.
International Search Report issued for corresponding PCT application PCT/GB2004/003820.

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