Syntheses of optically pure .alpha.-amino acids from 3-amino-2-o

Details Syntheses of optically pure .alpha.-amino acids from 3-amino-2-o Syntheses of optically pure .alpha.-amino acids from 3-amino-2-o

1990-10-23

1993-04-06

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549328, 562554, 562401, 562433, 562444, C07D23110, C07D30504

Patent

active

052005267

ABSTRACT:
A process for the preparation of optically pure .alpha.-amino acids comprising the nucleophilic ring-opening of 3-amino-2-oxetanone salts. N-Protected serine .beta.-lactones are deprotected to form heretofore unknown 3-amino-2-oxetanone and its corresponding salts. In turn these previously unknown 3-amino-2-oxetanone salts may be used in the synthesis of other novel or rare stereochemically-pure free amino acids.

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