Synthase of cereulide produced by Bacillus cereus , gene...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S006120, C435S069100, C435S183000, C435S320100, C536S023200, C536S024300, C536S024330, C536S091000

Reexamination Certificate

active

10513786

ABSTRACT:
It is intended to provide a method of conveniently and quickly detecting cereulide which is an emetic toxin produced byBacillus cereus. Cereulide is detected using the presence of cereulide synthase in a specimen as an indication. The presence of cereulide synthase is examined by detecting a nucleic acid encoding this enzyme or by an immunological method with the use of an antibody specific to the enzyme.

REFERENCES:
patent: 2001/0053519 (2001-12-01), Fodor et al.
patent: 2401268 (2001-10-01), None
patent: 19937241 (2001-02-01), None
patent: EP1508622 (2005-02-01), None
patent: WO99/51764 (1999-10-01), None
Ehling-Schulz et al. Identification and partial characterization of the nonribosomal peptide synthetase gene responsible for cereulide production in emeticBacillus cereus, Appl Environ Microbiol. Jan. 2005;71(1):105-13.
EMBL Accession No. Q5IRA4, Cereulide peptide synthetase, created May 10, 2005, alignment with SEQ ID No. 1.
N. Agata, et al.; “Bacillus cereusno Oto Dokuso Gosei Idenshi no Kaiseki;”Japanese Journal of Bacteriology; vol. 58; No. 1; Feb. 28, 2003; p. 142, WS-8-7.
N. Agata, et al.; “Production ofBacillus cereusemetic toxin (cereulide) in various foods;”Int. J. Food Microbiol.; vol. 73; No. 1; Feb. 2002; pp. 23-27.
Agata, N. et al; “A novel dodecadepsipeptide, cereulide isolated fromBacillus cereuscauses vacuole formation in Hep-2 cells”; FEMS Microbiol. Lett 121 (1994) , pp. 31-34.
Kathrin, M. et al; “Toxic and non-toxic strains of the cyanobacteriumMicrocystis aeruginosacontain sequences homologous to peptide synthetase genes”; FEMS Microbiol. Lett. 135 (1996); pp. 295-303.
Agata, N., et al; “Bacillus cercusno Oto Dokuso Gosei Idenshi no Kaiseki”; JP J.Bacteriol. vol. 58, No. 1 (Feb. 28, 2003) p. 142-WS-8-7 and English Translation.
Agata, N. et al; “Production ofBacillus cereusemetic toxin (cereulide) in various foods”; Int. J. Food. Microbiol., vol. 73, No. 1 (Feb. 2002); pp. 23-27.
Agata, N. et al; “A novel dodecadepsipeptide, cereulide, is an emetic toxin ofBacillus cereus”; FEMS Microbiol. Lett. 129 (1995) pp. 17-20.
Agata, N. et al; “Exotoxins ofBacillus sereusassociated with Food Poisoning” JP J.Bacteriol. 51 (1996), pp. 993-1002.
Agata, N. et al; “Growth Conditions of and Emetic Toxin Production byBacillus cereusin a Defined Medium with Amino Acids” Microbiol. Immunol. 43(1) (1999); pp. 15-18.
Agata, N. et al; “Production of an Emetic Toxin, Cereulide, Is Associated with a Specific Class ofBacillus cereus”; Current Microbiology; vol. 33 (1996); pp. 67-69.
Supplementary European Search Report dated Jan. 4, 2005.
XP-002336542—“Forward PCR primer used to detect expression of human ion-11 cDNA;” Nov. 19, 2001.
XP-002336543—“Sequence 15 from patent US5840536;” Oct. 6, 1999.
XP-002261512—Andersson et al; “A Novel Sensitive Bioassay for Detection ofBacillus cereusEmetic Toxin and Related Depsipeptide Ionophores;” Applied and Environmental Microbiology, Apr. 1988; pp. 1338-1343.
XP-002261514—Finlay et al; “Semiautomated Metabolic Staining Assay forBacillus cereusEmetic Toxin;” Applied and Environmental Microbiology, Apr. 1999; pp. 1811-1812.
XP-009021158—Schraft et al; “P-86-Identification of DNA Sequences to EmeticBacillus cereus;” 96th ASM General Meeting; May 19, 1996; p. 384.
XP-002336476—Haggblom et al; “Quantitative Analysis of Cereulide, the Emetic Toxin ofBacillus cereus, Produced under Various Conditions;” Applied and Environmental Microbiology, May 2002, pp. 2479-2483.
XP-002261513—Ripabelli et al; “Epidemiological typing ofBacillus cereusby amplified fragment length polymorphism;” Letters in Applied Microbiology, 2000, 30, pp. 358-363.
XP-002261511—Hansen et al; “Detection of EnterotoxicBacillus cereusandBacillus thuringiensisStrains by PCR Analysis;” Applied and Environmental Microbiology, Jan. 2001; pp. 185-189.
XP-002094834—Stachelhaus et al; “Modular structure of genes encoding multifunctional peptide synthetases required for non-ribosomal peptide synthesis;” FEMS Microbiology Letters 125 (1995) pp. 3-14.
XP-002265711—Agata et al; “Identification and Molecular Characterization of the Genetic Locus for Biosynthesis of the Emetic Toxin, Cereulide, ofBacillus cereus;” Abstract, American Society for Microbiology, 2002; p. 1.
Supplementary European Search Report dated Aug. 8, 2005.

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