Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-11-19
2008-08-12
Campell, Bruce (Department: 1648)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S332000, C514S333000, C514S340000, C514S342000, C546S255000, C546S256000, C546S268100, C546S269700
Reexamination Certificate
active
07410979
ABSTRACT:
The present invention relates to anti-HCV dihaloacetamide compounds in synergistic combination with an interferon and/or ribavirin and pharmaceutical compositions thereof for inhibition of the replication of HCV virus. The present invention also relates to the use of the compositions to inhibit HCV replication and/or proliferation and to treat or prevent HCV infections.
REFERENCES:
patent: 2852503 (1958-09-01), Edward et al.
patent: 3189447 (1965-06-01), Neugebauer et al.
patent: 3257203 (1966-06-01), Klupfel et al.
patent: 3335149 (1967-08-01), Preston
patent: 3910942 (1975-10-01), Neidermyer et al.
patent: 3964896 (1976-06-01), Neidermyer et al.
patent: 4087409 (1978-05-01), Preston
patent: 4405793 (1983-09-01), Fuchs et al.
patent: 4743521 (1988-05-01), Hoffmann et al.
patent: 4752324 (1988-06-01), Thomas et al.
patent: 4777258 (1988-10-01), Sitzmann
patent: 5151441 (1992-09-01), Mueller et al.
patent: 5256666 (1993-10-01), Mueller et al.
patent: 5463071 (1995-10-01), Himmelsbach et al.
patent: 5814627 (1998-09-01), Schwab et al.
patent: 6277830 (2001-08-01), Ganguly et al.
patent: 6355669 (2002-03-01), Yamauchi et al.
patent: 6403564 (2002-06-01), Ganguly et al.
patent: 6579880 (2003-06-01), Weidner-Wells et al.
patent: 6759538 (2004-07-01), Singh et al.
patent: 7157473 (2007-01-01), Singh et al.
patent: 7220745 (2007-05-01), Singh et al.
patent: 2002/0035156 (2002-03-01), Roniker et al.
patent: 2431171 (2002-06-01), None
patent: 392520 (1965-10-01), None
patent: 559 195 (1975-02-01), None
patent: 21 37 719 (1973-02-01), None
patent: 27 21 955 (1978-11-01), None
patent: 100 32 874 (2002-01-01), None
patent: 101 48 598 (2002-10-01), None
patent: 563686 (1993-03-01), None
patent: 0 776 894 (1997-06-01), None
patent: 92/7992 (1999-07-01), None
patent: 1 180 518 (2002-02-01), None
patent: 1 348 706 (2003-10-01), None
patent: 1 459 375 (1966-04-01), None
patent: 02-146048 (1990-06-01), None
patent: 03-122652 (1991-05-01), None
patent: 04124178 (1992-04-01), None
patent: WO 02/46186 (2002-06-01), None
patent: 93/17671 (1993-09-01), None
patent: 94/17059 (1994-06-01), None
patent: 95/24397 (1995-09-01), None
patent: 98/17652 (1998-04-01), None
patent: 98/47509 (1998-10-01), None
patent: 99/04390 (1999-01-01), None
patent: 99/20309 (1999-04-01), None
patent: 02/20436 (2000-03-01), None
patent: WO 00/23454 (2000-04-01), None
patent: 00/40242 (2000-07-01), None
patent: 00/45799 (2000-08-01), None
patent: 00/78726 (2000-12-01), None
patent: 01/74811 (2001-10-01), None
patent: 01/78648 (2001-10-01), None
patent: 02/46186 (2002-06-01), None
patent: 02/055025 (2002-07-01), None
patent: 03/029210 (2003-04-01), None
patent: WO 03/040112 (2003-05-01), None
patent: WO 2004/018463 (2004-03-01), None
patent: 2004/099164 (2004-11-01), None
patent: WO 2004/099164 (2004-11-01), None
patent: WO 2004/099165 (2004-11-01), None
patent: WO 2004/103366 (2004-12-01), None
patent: WO 2005/000308 (2005-01-01), None
patent: 2005/097760 (2005-10-01), None
Gatta et al., “Synthesis of [1,2,4] Triazoloquinazoline and [1,2,4] Triazolo-1,4-benzodiazepine derivatives,” Journal of Heterocyclic Chemistry, 1993, vol. 30, pp. 11-16.
Database Chemcats Online!, 1999m XP-002310049, Databased accession No. RN 247059-16-1.
Maybridge Hts, Order No. BTB 09742; RN 247059-16-1 Maybridge PLC, Trevillett, Tintagel, Cornwall, PL340HW, UK, Jan. 8, 2004, XP002297442.
STN File CA, Abstract 135:46129 & V.M. Barot et al., Asian Journal of Chemistry, 2001, 13(1), pp. 341-342.
STN File CA, Abstract 132:265141 & S.V Damie et al., Indian Journal of Heterocyclic Chemistry, 1999, 9(2), pp. 81-86.
STN File CA, Abstract 132:180505 & V.R. Naik et al., Asian Journal of Chemistry, 2000, 12(1), pp. 305-307.
STN File CA, Abstract 129:216539 & S.M. Naik et al., Oriental Journal of Chemistry, 1998, 14(1), pp. 167-168.
STN File CA, Abstract 126:74789 & M. Shah et al., Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1996, 35B(12), pp. 1282-1286.
STN File CA, Abstract 122:81186 & S.R. Modi et al., Oriental Journal of Chemistry, 1994, 10(1), pp. 85-86.
STN File CA, Abstract 118:191597 & T. Bandiera et al., Journal of Heterocyclic Chemistry, 1992, 29(6), pp. 1423-1428.
Kanbara et al., “Preparation of Soluble and Fluorescent Polly(arylene)s by 1,3-Dipolar Polycycloaddition and Properties of the Polymers,” Polymer Bulletin, vol. 36, pp. 673-679, 1996.
Ku et al., “Use of lodoacetylene as a Dipolarphile inn the Synthesis of 5-Iodoisoxazole Derivatives,” Organic Letters, vol. 3, No. 26, pp. 4185-4187, 2001.
Maybridge, plc, Trevillett, Tintagel, Catalogue No. RF01972, Cornwall PL34 OHW, England.
Maybridge, plc, Trevillett, Tintagel, Catalog No. RF01996, Cornwall PL34 OHW, England.
Gatta et al., “Synthesis of [1,2,4]Triazoloquinazoline and [1,2,4]Triazolo-1,4-benzodiazepine derivatives,” Journal of Heterocyclic Chemistry, 1993, vol. 30, pp. 11-16.
Roth et al., “Zur Kondensation von Chalkonoxyden mit Hydroxylamin,” Arch. Pharm., 1961, vol. 94, pp. 769-774.
Samula, “Oksymowanic Azachalkonow,” Roczniki Chemll, Ann. Soc. Chim. Polonorum, 1971, vol. 45, pp. 2063.
Samula, “Cyclization of Azachalcones and B-Hydroxyketones Oximes,” Roczniki Chemll, Ann soc. Chim, Polonorum, 1974, vol. 48, pp. 959-964.
Howe, et al., Nitrile Oxide Cycloaddition Routes to 2-(Isoxazoly)-benzoates and 2-(1,2,4-Oxadiazol-3-yl) benzoates, Heterocycl. Chem., 1982, vol. 19, No. 4, pp. 721-726.
Belgodere et al., “Sudies on Isomeric Pyridylisoxazoles,” Heterocycles, 1983, vol. 20, No. 3, pp. 501-504.
Batori et al., “Photoinduced Rig Transformation of Pyrido [1,2-b]pyridazinium-4-olate,” Tetrehedron, 1994, vol. 50, No. 16, pp. 4699-4708.
Campell Bruce
Horning Michelle
McDonnell Boehnen & Hulbert & Berghoff LLP
Rigel Pharmaceuticals Inc.
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