Synergistically active veterinary compositions and process for p

Details Synergistically active veterinary compositions and process for p Synergistically active veterinary compositions and process for p

1990-11-20

1992-06-09

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514311, A61K 3147, A61K 3700

Patent

active

051207117

ABSTRACT:
The invention relates to synergistically active veterinary compositions useful particularly for the treatment of mastitis and metritis. The invention further relates to a process for preparing these compositions. The compositions according to the invention comprise, based on 1 part by weight of 6,9,18-tris(2-aminoethyl) -15-benzyl-21-[.sup.- 2,8-bis(2-aminoethyl)-5-(1-hydroxyethyl) -15-methyl-4,7,10-trioxo-3,6,9-triazaheptadecanamido]-3-(1-hydroxyethyl)-1 2-isobutyl-1,4,7,10,13,16,19-heptaazacyclotricosane-2, 5,8,11,14,17,20-heptaone or a pharmaceutically acceptable acid addition salt thereof, 1 to 1000 parts by weight of 1-(2-chlorophenyl)-diphenylmethyl-1H-imidazole or 1 to 400 parts by weight of 2-methyl-5,7-dichloro-8-hydroxyquinoline, respectively, optionally in admixture with carriers and/or additives commonly used in the pharmaceutical industry.

REFERENCES:
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patent: 3929989 (1975-12-01), Bergt
patent: 3980778 (1976-09-01), Ayer et al.
patent: 4011312 (1977-03-01), Reuter et al.
patent: 4018918 (1977-04-01), Ayer et al.
patent: 4166118 (1979-08-01), Cosgrove et al.
patent: 4376787 (1983-03-01), Lentsch et al.
patent: 4600711 (1986-07-01), Swerczek
patent: 4650790 (1987-03-01), Simon et al.
Ernest Javetz M.D. Ph.D., Polymyxin, Neomycin, Bacitracin copyright 1956 pp. 14, 18.

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