Synergistic treatment of adult canine heartworm with thiacetarsa

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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424180, 424297, A61K 3171, A61K 31285

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active

044303297

ABSTRACT:
There is disclosed a method for the treatment of adult canine heartworm which involves treating a dog infected with adult heartworm first with thiacetarsamide and then, following a period of from 3 to 6 weeks, with ivermectin. The thiacetarsamide which has some activity against the adult heartworm has this activity potentiated or synergized by the ivermectin.

REFERENCES:
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4310519 (1982-01-01), Albers-Schonberg et al.
Journal of American Veterinary Medical Assoc. 142 pp. 23-26., (1963) Jackson.
Proceedings of Heartworm Symposium-1980, Jackson et al., (I) p. 137-140, Otto, Editor, Veterinary Medicine Publishing Co. (1981).
Proceedings of Heartworm Symposium-1980, Jackson et al., (II), pp. 153-156, Otto, Editor, Veterinary Medicine Publishing Co. (1981).
American Journal of Veterinary Research 40, Blair et al., pp. 1031-1032 (1979).
Journal of Helminthology 52, Campbell et al., pp. 308--310, (1978).
Proceedings of Heartworm Symposium-1980, pp. 182-184, Otto, Editor, Veterinary Medicine Publishing Co. (1981).

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