Synergistic therapeutic compositions comprising at least one lig

Details Synergistic therapeutic compositions comprising at least one lig Synergistic therapeutic compositions comprising at least one lig

1995-07-27

1998-06-16

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514563, A61K 31335, A61K 31195

Patent

active

057671486

ABSTRACT:
Pharmaceutical/dermatological compositions comprising (a) at least one first ligand displaying selective activity for the RXR receptors and (b) at least one second ligand displaying selective activity for the RAR-.alpha. receptor, are useful for modulating the proliferation and/or differentiation of HL-60 type cells, in particular for the systemic treatment of acute promyelocytic leukemia.

REFERENCES:
Proc Annu Meet Am Assoc Cancer Res; 33:A565-6 15-07-92, Sporn MB et al, p. 566, col. 1.
Blood, 84 (2) 1994, 446-452, Dawson et al, p. 448, Col. 2, Line 3, p. 450, Col. 2.
Nucleic Acids Res, Mar. 11, 1993, 21 (5), P1231-7, England, Schrader et al.
New Engl. J. Med. 1993, 329/3 (177-189), USA, p. 186, Col. 1, Line 3, Col. 2.

Affiliated with

Also associated with

Rating

Synergistic therapeutic compositions comprising at least one lig does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synergistic therapeutic compositions comprising at least one lig, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synergistic therapeutic compositions comprising at least one lig will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1726455