Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-05-17
1995-11-07
Travers, Russell
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514389, A61K 31425
Patent
active
054648505
ABSTRACT:
A family of solutions that can be used to calibrate one or more electrochemical sensors has been developed. These systems can be used to determine analytes in biological fluids, such as whole blood, serum, plasma and urine. Since these reagents require preservatives in order to make their shelf life and use life commercially feasible, a system of preservatives which exhibits unexpected synergy in antimicrobial capabilities has been identified. The preferred preservative system includes a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one; 2-methyl-4-isothiazolin-3-one; and 1,3-bis-(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione.
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Kabara, Jon J., Cosmetic and Drug Preservation, 1984, Marcal Dekker, Inc., N.Y., pp. 129-141, 165-190.
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Tagliaferro Dennis C.
Voo Liann
Wilson Joan B.
Ciba Corning Diagnostics Corp.
Morgenstern Arthur S.
Roesler Judith A.
Slepchuk, Jr. Nicholas I.
Travers Russell
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