Synergistic non-steroidal anti-inflammatory compounds and compos

Details Synergistic non-steroidal anti-inflammatory compounds and compos Synergistic non-steroidal anti-inflammatory compounds and compos

1984-07-26

1985-07-23

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514456, 514686, 514687, A61K 3112, A61K 31335, A61K 31355

Patent

active

045308446

ABSTRACT:
Non-steroidal anti-inflammatory compositions comprising a compound of the formula: ##STR1## wherein R.sub.1 is H or OH; and X, Y, X.sup.1 and Y.sup.1 represent hydrogen or halogen, such as chloro, fluoro, bromo, or iodo radicals, lower alkyl radicals such as C.sub.1 -C.sub.8 radicals, such as methyl, ethyl, propyl and butyl, lower haloalkyl radicals, such as trifluoro, trichloro or tribromo methyl radicals, and lower alkoxy radicals, such as C.sub.1 -C.sub.8 radicals such as methoxy, ethoxy, propoxy, and octyloxy radicals or combinations thereof and the salts thereof, in combination with a compound selected from the group consisting of vitamin E acetate, butylated hydroxytoluene, quercetin, nordihydroguaiaretic acid and mixtures thereof, said combination being contained in a pharmaceutically acceptable carrier.
A method of treating pain and inflammation is also disclosed.

REFERENCES:
patent: 4119713 (1978-10-01), Carosio
Chem. Abst. 98, (1983), --95533m.

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