Synergistic compositions for the selective control of tumor...

Details Synergistic compositions for the selective control of tumor... Synergistic compositions for the selective control of tumor...

2007-02-27

2007-02-27

Marschel, Ardin H. (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

Reexamination Certificate

active

10715818

ABSTRACT:
According to the invention, compositions are made available which have a strong cytotoxic effect which is largely selective on tumor tissue. The invention is based on the fact that certain benzoic acid derivatives have a strong synergistic effect as a mixture and destroy cancer cells selectively in a pH range of 7 or below, such as from 6.5 to 7.

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“Principles of Cancer Therapy”. Cecil's Textbook of Medicine ( Twenty-First Edition). W.B. Saunders Company, 2000. pp. 1060-1074.
Derwent, Database XP-002076797, See Abstract.
Robinson et al., Harefuah (1969). 76(1), 13 Abstract only.
Teicher et al., Cancer Chemother. Pharmacol. (1994), 33(6), 515-22 Abstract only.

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