Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-03-10
2000-12-19
Jordan, Kimberly
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514356, 514824, 514866, A61K 3155, A61K 3144
Patent
active
061628026
ABSTRACT:
A method for the treatment of a variety of cardiovascular disorders and related conditions in a mammal having at least one such disorder or condition is disclosed comprising treating the mammal with cotherapy comprising benazepril and amlodipine or pharmaceutically acceptable salts of either or both. Combination formulations of benazepril and amlodipine for use in the method are also disclosed.
REFERENCES:
patent: 4410520 (1983-10-01), Watthey
patent: 4572909 (1986-02-01), Campbell et al.
patent: 4703038 (1987-10-01), Garthoff et al.
patent: 4871731 (1989-10-01), Walker
patent: 4879303 (1989-11-01), Davison
patent: 4931430 (1990-06-01), Sudilovsky et al.
patent: 5037821 (1991-08-01), Horovitz
patent: 5093129 (1992-03-01), Horovitz et al.
patent: 5098910 (1992-03-01), Becker et al.
Clozel, "Effects of Nitrendipine and Cilazapril Alone or in Combination on Hemodynamics and Regional Blood Flows in Conscious Spontaneously Hypertensive Rats," J. Cardiovas. Pharm., vol. 12, No. 5, pp. 600-07 (1988).
Burges et al, Cardiovas. Drug Dev 8 (1) 25-44, 1990 (Abstract).
Clozel, J. Cardiovas. Pharm. 1988, 12(5), 600-607 (Abstract).
Dahlof et al, J. Cardiovas Pharm 1988 12, Supp 6 p. S104-108 (Abstract).
Zanchetti, J.Cardiovas. Pharm., 1988, 12 Supp. 4 p. S80-85 (Abstract).
Baba et al,Diabetologia Jan. 1989, 32(1) p. 40-44 (Abstract.
Maclean et al, J. Hum. Hypertens. Aug. 1988, 2(2) p. 127-132 (Abstract.
Dundee, J. Cardiovas. Pharmacol1988, 12 Supp 7, p. S85-88 (Abstract).
Bellet et al,Br. J. Clin. Pharmac. 1987, 24, 465-472.
Ikram et al, J. Amer. Coll. Cardiol. 17(2) 188A, 1991 Abstract.
Smith et al, FASEB vol. 5, No. 4, Mar. 11, 1991, p. A851, Abstract #2795.
Henis Marc M. J.
Papa Joseph
Hoxie Thomas
Jordan Kimberly
Tso Diane
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