Synergistic antimicrobial compositions containing a halogenated

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514689, A01N 3500, A01N 3700

Patent

active

055278264

ABSTRACT:
Compositions for controlling the growth of microorganisms in or on a product, material or medium comprising synergistically effective amounts of halogenated acetophenones, such as 2-bromo-4-hydroxyacetophenone, and at least one organic acid, its salt or ester are disclosed. Methods to control the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.

REFERENCES:
patent: 3193448 (1965-07-01), Buckman
patent: 3231509 (1966-01-01), Shema
patent: 3595665 (1971-07-01), Huitson et al.
Judefind et al., "The Identification of Acids. V. Para Halogen Phenacyl Ester," Para Halogen Phenacyl Esters, pp. 1043-1055, (Feb. 1920).
Munns et al., "1-(4-Hydroxyphenyl)-, 1-(2,4-dihydroxyphenyl)- and 1-(2,5-dihydroxyphenyl)-2-bromoethanones: new labels for determination of carboxylic acids by high-performance liquid chromatography with electrochemical and ultraviolet detection," Journal of Chromatography, 442 (1988) 209-218.
Abstract of Japanese Patent Application No. JP-066908 (Oct. 26, 1983).
The Merck Index, 10th Ed. (1983), pp. 155, 156, and 700.

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