Synergistic antibacterial compositions and method of treatment o

Drug – bio-affecting and body treating compositions – Plural fermentates of different origin

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A61K 3500

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active

045527636

ABSTRACT:
Antibiotic compositions comprising a 1-oxa .beta.-lactam antibiotic compound of the formula ##STR1## or pharmaceutically acceptable salts thereof and either tobramycin, amikacin or piperacillin exhibit synergistic activity against multiple-antibiotic-resistant organisms. The 1-oxa compound can be used in conjunction with tobramycin, amikacin or piperacillin in a method of treating infections caused by resistant organisms.

REFERENCES:
patent: 4138486 (1979-02-01), Narisada et al.
Modern Drug Encyclopedia, 14 ed., 1977 pp. 53-54.

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