Synergistic anti-plaque mixture with tetradecylamine and copper,

Details Synergistic anti-plaque mixture with tetradecylamine and copper, Synergistic anti-plaque mixture with tetradecylamine and copper,

1977-11-07

1979-03-27

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

424140, 424147, 424294, 424295, 424325, A61K 722

Patent

active

041466080

ABSTRACT:
A method and a composition for retarding plaque are disclosed. The composition includes a synergistic mixture of tetradecylamine in combination with copper, iron, nickel and/or cobalt, each of which may be used singly or in admixture in combination with the amine. The method generally includes applying a mixture of the tetradecylamine in combination with one or more of the above metals to the site of the plaque.

REFERENCES:
patent: 2876167 (1959-03-01), Manahan
patent: 3083143 (1963-03-01), Schmid et al.
patent: 3175951 (1965-03-01), Tucker et al.
patent: 3943267 (1976-03-01), Randol
Bass et al., J. Dent. Res. 54(5), 968-971 (1975), "Quantitative Studies of In Vitro Inhibition of Streptococcus Mutans Plaque Formation by Organic Amines".
Warner et al., J. Dent. Res. 55(1), 130-134 (1976), "A Physicochemical Approach to the Study of Amines as Antiplaque Agents".

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