Surgery – Means for introducing or removing material from body for... – Infrared – visible light – ultraviolet – x-ray or electrical...
Reexamination Certificate
2007-02-20
2007-02-20
Williams, Catherine S. (Department: 3763)
Surgery
Means for introducing or removing material from body for...
Infrared, visible light, ultraviolet, x-ray or electrical...
C604S500000, C607S088000
Reexamination Certificate
active
10677214
ABSTRACT:
The present invention is based on the discovery that electroporation of a photosensitive agent in a cell and subsequent activation of the agent provides more effective killing of the electroporated cell than cells exposed to a photosensitive agent alone. The invention provides a method and apparatus for inhibiting cell growth or enhancing cell death. The method includes providing a photosensitive agent to a cell; applying an electric pulse to the cell of a sufficient strength and duration to electroporate the cell with the photosensitive agent; and applying light of an activatable wavelength to the cell thereby activating the agent and inhibiting cell growth or enhancing cell death.
REFERENCES:
patent: 5079262 (1992-01-01), Kennedy et al.
patent: 5474528 (1995-12-01), Meserol
patent: 5674267 (1997-10-01), Mir et al.
patent: 6041252 (2000-03-01), Walker et al.
Berg Herman
Lambreya Maya
Bio Technology Law Group
Chambers Daniel M.
Genetronics Inc.
Murdock Douglas C.
Williams Catherine S.
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