Syn-isomer of thiazolyl intermediate and process for the prepara

Details Syn-isomer of thiazolyl intermediate and process for the prepara Syn-isomer of thiazolyl intermediate and process for the prepara

1994-04-25

1997-12-16

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540222, C07D27740

Patent

active

056987030

ABSTRACT:
The present invention provides a stable, crystalline syn-isomer of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetyl chloride hydrochloride substantially free of the anti-isomer and a process for the preparation thereof which may be used in an acylation process for the preparation of useful broad-spectrum antibiotics.

REFERENCES:
patent: 4203899 (1980-05-01), Ochiai et al.
patent: 4385181 (1983-05-01), Farge et al.
patent: 4406899 (1983-09-01), Aburaki et al.
patent: 4754031 (1988-06-01), Angerbauer et al.
patent: 4868294 (1989-09-01), Brundidge et al.
patent: 4910301 (1990-03-01), Kaplan et al.
patent: 4943631 (1990-07-01), Looker
Chemical Abstracts vol. 110, 389,79d p. 544 (1989).
English Translation of Czechoslovak patent CS 238,950 (1987).
Mandel, et al., Collect. Czech. Chem. Commun., 54: 1734-1745 (1989).

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