Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1978-10-23
1980-07-15
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
A61K 3140
Patent
active
042128803
ABSTRACT:
Symmetrically substituted pyromellic diimides are disclosed wherein the compounds are substituted with a variety of substituent groups. The symmetrically substituted compounds are useful for administration to ruminant animals to increase feed efficiency, shift volatile fatty acid production in the ruminant from acetate with an increase in the more energetically efficient propionate and butyrate and to suppress methane formation in the rumen. Compositions and methods of treatment utilizing said compounds as the active ingredient thereof are also disclosed.
REFERENCES:
patent: 2776889 (1957-01-01), Standen
patent: 3624212 (1971-11-01), Hennart
patent: 3738840 (1973-06-01), Anderson
Zhurnal Organicheshoi Khimii, (1966), vol. 2, No. 7, pp. 1265-1267.
Chemical Abstracts, vol. 84:135046 (1975); vol. 76, 72279q, 33987x (1972); vol. 59, 372c (1963); vol. 84, 150376a (1976); 84, 43982y (1976); 83:59699b (1975); 82:87103a (1975); 79:19700f (1973); 77:48850u (1972); 75:89332d (1971); 75:63340e (1971); 74:55134m (1971); 71:81122g (1969); 71:61062j (1969); 70:38694n (1969); 69:97581a (1968); 69:43899s (1968); 68:59326t (1968); 68:59329w; 67:116726d (1967); 65:13620f (1966); 63:4435f (1965); vol. 60:4054g (1964).
Fisher Michael H.
Kulsa Peter
Linn Bruce O.
Merck & Co. , Inc.
Rose David L.
Waddell Frederick E.
Westlake Harry E.
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