Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1980-10-02
1981-11-17
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544238, 544333, 544335, 544367, 546187, 546209, 548125, 2602444, 2602455, C07D41312, C07D27104
Patent
active
043012850
ABSTRACT:
This application provides a novel process for the synthesis of 3-[1(hydroxymethyl)-2-phenylethyl]-N-[(phenylamino)carbonyl]sydnonimine derivatives and novel hydrophobic and hydrophilic acyl derivatives thereof as pro-drug central nervous system stimulants.
REFERENCES:
patent: 3277108 (1966-10-01), Daeniker
Olovyanishinkiva et al., Khim. Geter. Soedin, vol. 2, (1978), pp. 170-175 and vol. 9, (1975), pp. 1198-1203.
Yashunskii et al., J. Med. Chem., vol. 14, (1971), pp. 1013-1015.
Polgar et al., Acta. Pharm. Hung., vol. 48, suppl., 23-24, (1978).
Polgar et al., Xenobiotica, vol. 9, (1979), pp. 511-520.
Kholodov et al., Mater. Resp. Rasshir, Konf. Farmecol. Gruz., 2nd 1977, pp. 84-85.
American Home Products Corporation
Jackson Richard K.
Jiles Henry R.
Ramsuer R. W.
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