Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2011-02-08
2011-02-08
Weber, Jon P (Department: 1657)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
C424S093700
Reexamination Certificate
active
07883892
ABSTRACT:
The present invention provides swine cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple cell types. Also provided are methods of isolation and culture, as well as uses for the cells, such as xenogeneic transplantation and/or tissue repair.
REFERENCES:
patent: 5843425 (1998-12-01), Sachs et al.
patent: 6030833 (2000-02-01), Seebach et al.
patent: 6090625 (2000-07-01), Abuljadayel et al.
patent: 7015037 (2006-03-01), Furcht et al.
patent: 2003/0157078 (2003-08-01), Hall et al.
patent: WO 96/23870 (1996-08-01), None
patent: WO-2006047743 (2006-05-01), None
patent: WO-2006047743 (2006-05-01), None
patent: WO-2006047743 (2006-11-01), None
Ringe J. et al. Porcine mesenchymal stem cells: Induction of distinct mesenchymal cell lineages, Cell Tissue Res (2002) vol. 307, pp. 321-327.
Kovacevic, M., et al., “Erythroid Progenitor Cells from Pig Bone Marrow and Peripheral Blood”,The Veterinary Journal, 158, www.idealibrary.com,(1999),196-203.
Communication and Accompanying Form 1149 dated Oct. 2, 2007 in related U.S. Appl. No. 11/238,234.
Second Communication and Accompanying Form PTO/SB/08b dated Dec. 24, 2008 in related U.S. Appl. No. 11/238,234.
Talbot et al., “Alkaline phosphatase staining of pig and sheep epiblast cells in culture” Molecular Reproduction and Development, 36:139-147 (1993).
Notarianni et al., “Maintenance and Differentiation in culture of pluripotential embryonic cell lines from pig blastocysts” J. Reprod Fert., Suppl. 41:51-56 (1990).
Notarianni et al., “Derivation of pluripotent, embryonic cell lines from the pig and sheep” J. Reprod. Fert., Suppl. 43:255-260 (1991).
Piedrahita et al., “Influence of feeder layer type on the efficiency of isolation of porcine embryo-derived cell lines” Theriogenology, 34:865-877 (1990).
Aldous et al., “Flawed stem cell data withdrawn” New Scientist; ( Feb. 15, 2007).
Aldous et al., “Fresh questions on stem cell findings” New Scientist; (Mar. 24, 2007).
Check “Stem cell paper corrected” Nature; 447:763 (2007) and Jiang et al., “Pluripotency of mesenchymal stem cells derived from adult bone marrow” Erratum in Nature; 447:879-880 (2007).
Chi, “Adult stem cell figure retracted” The Scientist; (Jun. 13, 2007).
Glenn, “Paper on versatility of adult stem cells comes under question” The Chronicle; (Feb. 26, 2007).
Holden, “Stem Cells. Controversial marrow cells coming into their own?” Science; 315:760-761 (2007).
Jiang et al., “Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain” Exp. Hematol.; 30:896-904 (2002).
Jiang et al., “Pluripotency of mesenchymal stem cells derived from adult marrow, Supplemental Information for Verfaillie Corrigendum” Nature; 418:41-49 (2002).
Lerner et al., “Stem cell study was flawed, U panel finds” Star Tribune; (Feb. 27, 2007).
Noonan, “Limitations on the usefulness of adult stem cells” Patent Docs (Feb. 28, 2007).
Pincock, “Adult stem cell report questioned” The Scientist (Feb. 26, 2007).
Reyes et al., “Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells” Blood; 98:2615-25 (2001).
Serafini et al., “Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cell” J. Exp. Med.; 204:129-139 (2007).
Verfaillie, “Letter to the Editor” Experimental Hematology; (2007).
Giles, J., “The trouble with replication” Nature, 422:344-347 (2006).
Verfaillie, C.M., Multipotent adult progenitor cells: an update: Novartis Found Symp., 254:55-65 (2005).
Reya et al., Stem Cells, cancer, and cancer stem cells: Nature; 414:150-111 (2001).
Bjornson et al., “Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo” Science; 283:534-537 (1999).
Bouwens, L., “Transdifferentiation versus stem cell hypothesis for the regeneration of islet beta-cells in the pancreas” Microscopy Research and Technique; 43:332-336 (1998).
Reyes et al., “Origin of endothelial progenitors in human postnatal bone marrow” J. Clin. Invest.; 109:1-10 (2002).
Reyes et al., “Characterization of multilineage mesodermal progenitor cells in adult marrow” Abstract No. 124, American Society for Hematology (2001).
Reyes et al., “Skeletal smooth and cardiac muscle differentiation from single adult marrow derived mesodermal progenitor cells” Abstract No. 2610, American Society for Hematology (2001).
Reyes et al., “In vitro and in vivo characterization of neural cells derived from mesenchymal stem cells” Abstract 2126, American Society for Hematology (2001).
Gupta et al., “Human bone marrow derived mesodermal progenitor cells (MPC) in vitro correct the biochemical abnormality in Hurler Syndrome” Abstract 1199, American Society for Hematology (2001).
Reyes et al., “Endothelial cells generated from human marrow derived mesenchymal stem cells (MSC)” Abstract No. 2276, American Society for Hematology (2001).
Zhao et al., “Immunohistochemical identification of multipotent adult progenitor cells from human bone marrow after transplantation into the rat brain” Brain Res Brain Res Protoc; 11:38-45 (2003).
Schwartz, R., “Multipotent adult progenitor cells from bone marrow differentiate into hepatocyte-like cells” J. Clin. Invest.; 109:1291-1302 (2002).
Zhao et al., “Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats” Exp Neurol; 174:11-20 (2002).
Qi et al., “Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells” Nat. Acad. Sci. USA; 100:3305-3310 (2003).
Verfaillie, C. “Investigator Profile” Journal of Hematotherapy and Stem Cell Research; 11:441-444 (2002).
Verfaillie et al., “Stem cells: hype and reality” Hematology (Am Soc Hematol Educ Program); 369-391 (2002) PMID: 12446433 [PubMed—in process].
Verfaille, C., “Optimizing hematopoietic stem cell engraftment: a novel role for thrombopoeitin” J. Clin. Invest.; 110:303-304 (2002).
Verfaillie, C.M., “Meeting Report on an NHLBI Workshop on ex vivo expansion of stem cells, Jul. 29, 1999, Washington D.C. National Heart Lung and Blood Institute” Exp. Hematol.; 28:361-4 (2000).
Punzel et al., “The myeloid-lymphoid initiating cell (ML-IC) assay assesses the fate of multipotent human progenitors in vitro” Blood; 93:3750-3756 (1999).
Roy et al., “Expression and function of cell adhesion molecules on fetal liver, cord blood and bone marrow hematopoietic progenitors: implications for anatomical localization and developmental stage specific regulation of hematopoiesis” Exp. Hematol.; 27:302-312 (1999).
Verfaillie, C., “Stem cells in chronic myelogenous Leukemia” Hematol. Oncol. Clin. North Am.; 11:1079-114 (1997).
Prosper et al., “Phenotypic and functional characterization of long-term culture-initiating cells present in peripheral blood progenitor collections of normal donors treated with granulocyte colony-stimulating factor” Blood; 15:2033-2042 (1996).
Lodie et al., “Systematic analysis of reportedly distinct populations of multipotent bone marrow-derived stem cells reveals a lack of distinction” Tissue Engineering; 8:739-751 (2002).
Wade et al., “Scientists herald a versatile adult cell” The New York Times on the Web, Jan. 25, 2002.
Eglitis et al., “Hematopoietic cells differentiate into both microglia and macroglia in the brain of adult mice” Proc. Natl. Acad. Sci. USA; 94:4080-85 (1997).
Kopen et al., “Marrow stromal cells migrate thr
Verfaillie Catherine M.
Zeng Lepeng
Zhang Jianyi
Regents of the University of Minnesota
Singh Satyendra K
Tarolli, Sundheim Covell & Tummino L.L.P.
Weber Jon P
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